The Francis Crick Institute
Postdoctoral Training Fellow in Computational Biology – Fröhlich Lab
The Fröhlich lab develops models to describe the dynamic behaviour of biological systems combining techniques from mathematical modelling and machine learning. We develop computational tools to build and train these models on experimental data and apply these tools to understand the regulatory principles that determine the dynamic response to external perturbations. More details about the group and our research interests can be found here: www.frohlichlab.com
The successful candidate will join a growing, multi-disciplinary team of scientists with the opportunity to contribute own ideas and help shape the research profile of the lab. Research projects will be supported by a vibrant, multi-disciplinary scientific community at the Crick, with ample opportunities for internal and external collaborations. Moreover, the candidate will have access to state-of-the-art core facilities at the Crick, including the High-Performance-Computing platform, and rich structured career development and networking opportunities.
Several research directions are being pursued and the successful candidate will have the freedom to develop and undertake their own independent research projects within the scope of the lab’s interests. Topics include development of hybrid models that use machine learning methods to contextualize ordinary differential equation (ODE) models using (single-cell) omics and imaging data; and the development of neural-network-based coarse-graining of protein-structure-based models.
The post holder will be responsible for:
- Leading and developing specific research projects
- Developing and maintaining computational tools for the contextualization of ODE models
- Applying methods to biological data and interpreting results
- Collaborating with national and international partners
- Presenting work at lab meetings as well as national and international meetings
- Publishing scientific results
- Assisting in training graduate students and other members of the laboratory
The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.
An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.
The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.
The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.
- If you are interested in applying for this role, please apply via our website.
- The closing date for applications is 9.12.2022.
- All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.